Among the many series that have been a setting for Scooby-Doo and the gang, there was the 1985 show, THE 13 GHOSTS OF SCOOBY-DOO, an adventure series starring Shaggy, Scooby, and Daphne, accompanied by Scrappy and a young con-artist named Flim-Flam. In this series, Shaggy had opened a chest of demons, releasing the 13 ghosts inside. Due to the wording of the curse, only the person who released the ghosts could put them back in -- so a globe-spanning series began, with their mystic mentor, Vincent Van Ghoul (voiced by VINCENT PRICE), leading them from one caper to the next.
This series was unlike previous incarnations of the show, because the ghosts were not people in rubber masks using hidden rope-and-pulley systems, but actual spirits. However, during the course of the show's run, they only captured twelve of the ghosts.